Anti-EGFR (phospho-Y992) Antibody

This phospho-specific polyclonal reagent from Antibodies.com selectively recognizes EGFR only when tyrosine 992 is phosphorylated, a major autophosphorylation site that couples ligand binding to downstream signaling cascades such as PLC-gamma recruitment. Raised in rabbit and supplied as an unconjugated antibody at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol, the antibody is validated for Western blot, immunohistochemistry, and immunofluorescence workflows on human and rat samples, making it a practical tool for tracking EGFR activation in cell signaling studies, tumor biology research, and investigations of receptor tyrosine kinase pathway dynamics. Each vial contains 100 µl of ready-to-use antibody, and the glycerol-containing buffer supports convenient storage at -20 °C with minimal freeze-thaw impact on antibody performance. Researchers studying EGF-stimulated signaling, receptor internalization, or mutant EGFR variants in oncology models will find this reagent useful for dissecting phosphorylation-dependent events at this specific tyrosine residue.