Anti-EGFR (phospho Y1092) Antibody

This rabbit polyclonal reagent from Antibodies.com is raised against the Epidermal Growth Factor Receptor (EGFR) and specifically recognizes the receptor only when phosphorylated at tyrosine 1092 (Y1092), a C-terminal autophosphorylation site linked to active EGFR kinase signaling. The unconjugated IgG antibody is provided as a 50 µl aliquot and is validated for Western blot (WB) applications on human samples, including cell lysates and tumor tissue. Y1092 phosphorylation correlates with receptor activation and is widely monitored in studies of downstream MAPK and PI3K-AKT pathway activity, receptor tyrosine kinase biology, and oncogenic signaling in carcinomas such as lung, breast, colon, and glioblastoma. The polyclonal format produces a broad immune response directed at the phospho-Y1092 epitope, supporting reproducible detection of activated EGFR across basic research, translational oncology, and signal transduction investigations.