Anti-EGFR (phospho T678) Antibody

This rabbit polyclonal antibody from Antibodies.com is supplied as an unconjugated IgG in a 50 µl vial and was raised against the epidermal growth factor receptor (EGFR) phosphorylated at threonine 678. Validated for western blot and reactive with human EGFR, the reagent lets researchers monitor site-specific phosphorylation of this receptor in cell-based studies.

EGFR is a transmembrane receptor tyrosine kinase central to proliferation, differentiation, and survival signaling, and phospho-specific antibodies are a standard tool for distinguishing activated receptor pools from total receptor levels in immunoblotting experiments. The unconjugated format means the antibody can be paired with a broad choice of secondary reagents and detection chemistries, including HRP- or fluorophore-conjugated secondaries, depending on the workflow. To preserve activity, aliquot the vial upon arrival to limit freeze-thaw cycles; working stocks can be kept refrigerated, with long-term storage at -20°C in single-use portions. For research use only.