Anti-EGFR (H672) Antibody

This unconjugated rabbit polyclonal antibody from Antibodies.com targets the epidermal growth factor receptor, a 170 kDa transmembrane tyrosine kinase that governs proliferation and survival signaling in epithelial cells and is widely studied as an oncogenic driver. Supplied as 100 µl at 1 mg/ml in phosphate buffered saline containing 0.05% sodium azide at approximately pH 7.2, the reagent is validated for western blot and immunohistochemistry on both human and mouse specimens. Researchers apply it to characterize receptor expression in tumor biopsies, investigate downstream RAS-MAPK and PI3K-AKT pathway activation, and profile EGFR levels in cell line panels. The polyclonal format provides recognition of multiple epitopes on the target, which can be advantageous when detecting both full-length receptor and processed variants in fixed or lysed samples.