Anti-EGFR Antibody

Epidermal Growth Factor Receptor (EGFR) is a 170 kDa transmembrane glycoprotein belonging to the ErbB family of receptor tyrosine kinases, encoded at chromosome 7p11.2. This receptor drives key signaling cascades governing cell proliferation, survival, and differentiation, and its dysregulation is a focal point in cancer biology research across lung, breast, colorectal, and glioblastoma tumor models.

This polyclonal reagent from Antibodies.com was raised in rabbit and is supplied as an unconjugated preparation in a 100 µl vial, intended for research use only. It recognizes EGFR from human, mouse, and rat origins, enabling consistent antibody-based detection across multiple model systems. The reagent is validated for western blot, immunohistochemistry, immunofluorescence, and ELISA workflows, supporting both total protein quantification and spatial localization studies in fixed tissue and cell preparations.

Aliquot upon first use and store at -20 degrees C, avoiding repeated freeze-thaw cycles to preserve binding performance. Each lot is affinity-purified and accompanied by reactivity data to help researchers benchmark band patterns on western blot membranes and signal intensity in immunofluorescence imaging.