Anti-EGFR (Ab-1092) Antibody

EGFR (Epidermal Growth Factor Receptor) is a transmembrane receptor tyrosine kinase that drives proliferative and survival signaling in epithelial tissues and is a frequent subject of oncology research. This reagent is a rabbit polyclonal antibody preparation raised against a synthetic peptide corresponding to the region surrounding residue 1092 of the EGFR sequence, allowing detection of the receptor across multiple assay formats.

Distributed by Antibodies.com, the antibody is supplied as a 100 µl aliquot in an unconjugated format, ready for use with standard HRP- or fluorophore-labeled secondary reagents. It has been validated for Western blot and immunohistochemistry workflows and shows reactivity against both human and rat EGFR, supporting translational studies that bridge rodent model findings with human tissue analysis.

For optimal stability, the vial should be stored at -20 °C in working aliquots to limit repeated freeze-thaw cycles. Brief centrifugation before opening will recover the full liquid volume from the cap and sides of the tube. Researchers should include appropriate positive and negative controls, such as EGFR-overexpressing carcinoma lysates for Western blot and normal epithelial tissue sections for immunohistochemistry, to confirm assay specificity in each run.