Anti-Eg5 / KIF11 Antibody

This unconjugated mouse monoclonal antibody from Antibodies.com targets the kinesin family member KIF11, also known as Eg5, a plus-end directed microtubule motor protein required for bipolar mitotic spindle assembly during cell division. The reagent is supplied as a 100 µl purified preparation in a buffer containing 0.1 M Tris-Glycine at pH 7.4, 150 mM NaCl, 50% glycerol, and 0.2% sodium azide as a preservative, and should be stored refrigerated to preserve activity across multiple freeze-thaw cycles. Validated applications include Western blot, immunocytochemistry, and immunoprecipitation, with reactivity confirmed against human Eg5 / KIF11. Researchers studying mitotic spindle dynamics, chromosome segregation, and cell cycle regulation use this reagent to probe Eg5 expression and localization in dividing cells, making it a useful tool for projects that screen candidate mitotic inhibitors or characterize microcephaly-associated variants of the KIF11 gene.