Anti-EFNB2 Antibody

Ephrin-B2 (encoded by EFNB2) is a membrane-anchored ligand for Eph receptors that drives embryonic vascular patterning, angiogenesis, axon guidance, and contact-mediated cell migration. EFNB2 participates in bidirectional Eph/ephrin signaling, functioning both as a surface ligand and as a signal-transducing receptor that reshapes the cytoskeleton and repels neighboring cells at tissue boundaries. This rabbit IgG polyclonal reagent from Antibodies.com enables detection of these dynamics in standard immunolabeling workflows.

Supplied unconjugated at 100 µl per vial, the antibody supports flexible pairing with the researcher's secondary reagents of choice. It has been validated for western blot, immunohistochemistry, and immunofluorescence staining on human, mouse, and rat samples, suiting cross-species projects in vascular biology and neurodevelopment. The polyclonal format recognizes multiple epitopes on the EFNB2 protein, improving signal robustness on fixed tissue sections and denatured lysates alike.

For reproducible performance, aliquot the vial upon arrival, store at -20 °C, and minimize freeze-thaw cycles to protect binding activity. The product is intended for research use only and is handled as a single-use working stock per aliquot session.