Anti-EFNB1 Antibody

Used to probe endogenous ephrin-B1 in human and mouse samples, this rabbit polyclonal IgG reagent from Antibodies.com is supplied as an unconjugated liquid fraction in a 50 µl vial suited to western blot detection of the ~38 kDa transmembrane ligand. EFNB1 encodes a membrane-anchored ephrin that engages EphB receptors to drive bidirectional signalling, patterning axon guidance, neural crest cell migration, and segmental tissue boundaries during embryogenesis. Loss-of-function mutations in the X-linked EFNB1 locus cause craniofrontonasal syndrome, supporting the protein's use as a marker in developmental biology and human genetics research. The antibody is affinity purified from rabbit serum; refrigerate upon arrival and avoid repeated freeze-thaw cycles to preserve activity. Researchers characterising ephrin-B1 phosphorylation, receptor clustering, or boundary formation detect endogenous EFNB1 expression with this polyclonal reagent by immunoblotting.