Anti-EFNA5 Antibody

In neuroscience and vascular biology research, the GPI-anchored ephrin-A5 ligand directs axon pathfinding, neural crest cell migration, and tissue boundary formation through engagement with EphA family receptor tyrosine kinases, with additional roles in retinal topographic mapping and vascular patterning during embryonic development.

The polyclonal reagent distributed by Antibodies.com is raised in rabbit, supplied as 100 µl of unconjugated antiserum, and validated for Western blot, immunohistochemistry, and immunofluorescence on human, mouse, and rat specimens. This cross-species reactivity supports comparative studies of Eph/ephrin signaling in developmental neurobiology and tumor microenvironment research, where altered EFNA5 expression has been investigated in glioma invasion and epithelial tumor progression.