Anti-eEF2K (G358) Antibody

Raised in rabbit, this polyclonal primary antibody from Antibodies.com targets eukaryotic elongation factor 2 kinase (eEF2K), a calcium/calmodulin-dependent kinase that downregulates protein translation by phosphorylating elongation factor 2. The reagent was raised against a region encompassing residue G358 of the eEF2K protein, allowing detection of the kinase in tissues from multiple species.

Validated for immunohistochemistry (IHC) on human, mouse, and rat specimens, the unconjugated reagent is supplied at 1 mg/ml in phosphate buffered saline (PBS) containing 0.05% sodium azide at approximately pH 7.2, packaged as a 50 ul vial. The antibody is suited to localizing eEF2K expression in formalin-fixed paraffin-embedded tissue sections, supporting studies in cancer signaling, neurodegeneration, and translational control where eEF2K activity has been implicated.

For best results, refrigerate the vial upon arrival and aliquot to limit freeze-thaw cycles; protect from light to preserve reagent integrity. The polyclonal format recognizes multiple epitopes on the target, helping to detect the kinase across varying expression levels in tissue specimens.