Anti-EDN1 Antibody

Endothelin-1 (EDN1) is a 21-amino-acid vasoactive peptide secreted primarily by vascular endothelial cells and implicated in vasoconstriction, smooth muscle proliferation, and inflammatory signaling cascades. The Antibodies.com polyclonal reagent raised in rabbit is affinity-purified against the EDN1 sequence and validated for western blot and immunohistochemistry workflows, with verified reactivity against human, mouse, and rat samples.

Supplied as 100 µl of unconjugated antibody at 1 mg/ml in PBS buffer containing 0.1% sodium azide and 50% glycerol, this Primary Antibodies reagent is ready to dilute into standard blotting and staining protocols. The glycerol-containing formulation provides freeze-thaw stability for repeated use, while sodium azide preserves the solution for short-term refrigerated storage at 4 °C. Each vial offers sufficient volume for multiple membrane probing experiments or a panel of fixed-tissue sections.

Researchers investigating cardiovascular disease models, pulmonary hypertension, renal pathology, or cancer-associated angiogenesis commonly apply EDN1 antibodies to map peptide expression across tissue sections and to confirm protein-level changes observed in transcriptomic studies. The polyclonal nature of the reagent enables recognition of multiple epitopes, supporting robust signal in both denaturing western blot conditions and fixed-tissue IHC preparations across a range of model organisms.