Anti-EDAR Antibody

This rabbit polyclonal IgG antibody from Antibodies.com specifically targets EDAR (Ectodysplasin A Receptor), a TNF receptor superfamily member that drives ectodermal appendage development including hair follicles, teeth, and sweat glands. Researchers investigating hypohidrotic ectodermal dysplasia—a condition linked to EDAR signaling defects—use this unconjugated reagent to probe human tissue lysates via western blot.

The 100 µl vial contains affinity-purified antibody suitable for chemiluminescent detection on PVDF or nitrocellulose membranes. As a polyclonal reagent, it provides broader epitope coverage than monoclonal alternatives, which can be advantageous when mapping variant expression across patient-derived samples. The unconjugated format also gives flexibility to pair with HRP-, biotin-, or fluorophore-labeled secondary antibodies depending on the western blot detection platform.

Storage and handling: the antibody is supplied frozen; store aliquots at -20 °C or colder and avoid repeated freeze-thaw cycles to preserve reactivity. The IgG isotype designation guides selection of compatible secondary reagents for the chosen detection chemistry.