Anti-EAF2 Antibody

This polyclonal antibody from Antibodies.com targets EAF2 (ELL-Associated Factor 2), a transcription elongation factor that modulates RNA polymerase II activity and has documented roles in apoptosis regulation and tumor suppression pathways, particularly in prostate tissue.

Raised in rabbit and supplied at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol, the unconjugated reagent is validated for western blot, immunohistochemistry, and immunofluorescence workflows across human, mouse, and rat sample types. Each vial contains 100 µl of antibody for probing endogenous EAF2 expression in cell lysates and fixed tissue sections.

EAF2 interacts with ELL family proteins and has been studied in the context of castration-resistant prostate cancer and androgen receptor signaling. Laboratories investigating transcription elongation, chromatin regulation, and prostate oncogenesis use this reagent to assess EAF2 protein levels and subcellular localization across experimental models, including studies of castration-induced apoptosis and ELL-mediated transcriptional control.