Anti-Dynein LC 1 Antibody

Dynein light chain 1 (DYNLL1, also called LC8) is a small ~10 kDa accessory subunit of the cytoplasmic dynein motor complex, where it supports microtubule-based retrograde transport of vesicles, organelles, and protein cargoes along axons and within dividing cells. Beyond its role in cargo trafficking, DYNLL1 is studied for its involvement in apoptosis regulation, mitotic spindle assembly, and several neurodegenerative disease models.

This unconjugated rabbit polyclonal reagent from Antibodies.com is raised against Dynein LC 1 and is validated for Western blot (WB), immunohistochemistry (IHC), and ELISA workflows. The antibody shows reactivity with human and mouse samples, making it useful for cross-species studies of cytoskeletal motor function and intracellular transport. Each vial contains 100 µl of polyclonal antiserum, supplied as a liquid stock ready for dilution into standard blocking and incubation buffers.

Researchers in neuroscience, cell biology, and cancer biology use this reagent to assess dynein subunit expression in tissue lysates, fixed sections, and recombinant protein preparations. The polyclonal format increases the chance of recognizing multiple epitopes on the 10 kDa light chain, which is helpful when probing for post-translational modifications or truncated isoforms.