Anti-DUSP6 (L76) Antibody

Targeting dual specificity phosphatase 6 (DUSP6), also referred to as MKP-3, this rabbit polyclonal reagent from Antibodies.com recognizes a mitogen-activated protein kinase phosphatase that selectively dephosphorylates ERK1 and ERK2. Supplied as an unconjugated antibody at 1 mg/ml in phosphate buffered saline with 0.05% sodium azide at approximately pH 7.2, the antibody is validated for western blot and immunohistochemistry workflows on human, mouse, and rat samples. Each vial contains 100 µl of stock suitable for aliquoting into smaller working portions; store refrigerated and protect from light to preserve binding activity through repeated use. The polyclonal format offers multi-epitope recognition of the DUSP6 protein, supporting research on MAPK pathway feedback inhibition, fibroblast growth factor signal regulation, and tumor biology contexts in which DUSP6 has been explored as a downstream readout of RAS-RAF-MEK-ERK pathway activation.