Anti-DUSP6 Antibody

Recombinant rabbit monoclonal reagent from Antibodies.com that detects dual-specificity phosphatase 6 (DUSP6), a cytoplasmic MAPK phosphatase which dephosphorylates ERK1/2 and acts as a feedback regulator of the RAS-RAF-MEK-ERK signaling cascade. The unconjugated antibody has been validated for western blot, immunocytochemistry/immunofluorescence, immunohistochemistry, and flow cytometry, and it cross-reacts with human, mouse, and rat samples, supporting research into cancer cell signaling, developmental biology, and pathway analysis of KRAS-driven tumor models.

Supplied as 100 µl in a vial format, the product is formulated in 1*TBS (pH 7.4) with 1% BSA, 40% glycerol, and 0.05% sodium azide as preservative. Store at -20 °C and aliquot to limit freeze-thaw cycles. The unconjugated format permits flexible pairing with secondary antibodies and chromogenic or fluorescent detection chemistries, supporting phosphorylation-state studies, subcellular localization work, and immunophenotyping of MAPK-pathway components in primary cells and cultured lines.