Anti-DUSP19 Antibody

This rabbit polyclonal IgG reagent from Antibodies.com specifically recognizes DUSP19, a nuclear dual-specificity phosphatase that regulates stress-activated MAP kinase signaling by dephosphorylating both phosphotyrosine and phosphoserine/phosphothreonine residues on MAPK substrates. Provided as 50 µL of unconjugated antiserum, the antibody is validated for western blot detection of the approximately 24 kDa endogenous target in human, mouse, and rat samples, supporting cross-species experimental designs with a single reagent. The polyclonal format yields recognition of multiple epitopes on DUSP19, improving detection when target expression is low and tolerating minor sequence variation between species. Investigators working on innate immunity, JNK/p38 pathway regulation, and inflammatory signaling apply this primary antibody to cell lysates and tissue homogenates by immunoblotting. Freeze-thaw cycles should be minimized by aliquoting on first use, and the unconjugated format allows pairing with HRP- or fluorophore-conjugated secondary antibodies chosen by the laboratory.