Anti-DUSP16 Antibody

This rabbit polyclonal reagent from Antibodies.com targets DUSP16 (Dual Specificity Phosphatase 16), a dual-specificity phosphatase that dephosphorylates both phosphotyrosine and phosphoserine/phosphothreonine residues on MAPK family members, including JNK and p38. The unconjugated antibody is supplied in a 100 µl vial as an affinity-purified preparation raised in rabbit and validated for western blot (WB) and immunofluorescence (IF) workflows on human and mouse samples.

DUSP16, also referenced as MKP-7, plays a regulatory role in stress-activated kinase signaling, T-cell receptor signaling, and apoptosis, making it a relevant target for studies of innate immunity, cytokine response, and cellular stress pathways. Researchers investigating JNK pathway attenuation, neuronal stress responses, or immune cell activation use this reagent to probe endogenous DUSP16 expression in cell lysates and fixed tissue sections.

For long-term storage, keep the vial at -20 °C in working aliquots to limit freeze-thaw cycles, and avoid repeated exposure to room temperature. The host species is rabbit, clonality is polyclonal, and the reagent is provided unconjugated, allowing flexible downstream labeling with secondary antibodies compatible with either WB or IF detection chemistries.