Anti-DUSP14 Antibody

The Anti-DUSP14 polyclonal antibody from Antibodies.com is a rabbit-derived reagent raised against Dual Specificity Phosphatase 14, a dual-specificity phosphatase that modulates MAPK signaling cascades by dephosphorylating ERK, JNK, and p38 substrates. The reagent is supplied at 1 mg/mL in PBS containing 0.1% sodium azide and 50% glycerol, with a 100 µL pack size that supports multiple immunoblotting experiments.

This unconjugated antibody was validated for Western blot detection of endogenous DUSP14 in human, mouse, and rat samples, enabling researchers to study the phosphatase's role in T-cell receptor signaling, innate immunity, and tumor biology contexts including hepatocellular carcinoma where DUSP14 has been linked to proliferation and stress-response pathways. The predicted target band migrates near 22 kDa.

For reliable results, store the vial at -20 °C, avoid repeated freeze-thaw cycles, and dilute into standard TBST blocking buffer. The glycerol-containing formulation protects the antibody from degradation and supports short-term handling at refrigerated temperatures without compromising binding activity. Researchers should aliquot the stock upon first thaw to preserve long-term performance across multiple blotting runs.