Anti-DTX3 Antibody

This polyclonal antibody from Antibodies.com targets human DTX3, also known as Deltex E3 Ubiquitin Ligase 3, a member of the Deltex family of E3 ubiquitin ligases that modulates Notch receptor signaling. Raised in rabbit, the reagent is supplied as an unconjugated antiserum at 100 µl volume, validated for Western blot and immunohistochemistry workflows on human-derived samples. Deltex proteins contribute to ubiquitin-dependent regulation of Notch pathway activity and have been studied in connection with lymphocyte signaling and innate immune responses, where DTX3 and its close paralog DTX3L influence substrate ubiquitination patterns. Researchers investigating Notch signal transduction, E3 ligase activity, or related post-translational control mechanisms can detect endogenous DTX3 in lysates and fixed tissue sections with this reagent. The product is supplied as a 100 µl aliquot and is intended for research use only.