Anti-DRD3 Antibody

Dopamine Receptor D3 (DRD3) is a D2-like G protein-coupled receptor predominantly expressed in limbic regions of the brain, where it modulates dopaminergic signaling tied to cognition, reward processing, and motor control. This rabbit polyclonal antibody from Antibodies.com targets DRD3 for detection in human samples and is validated for Western blot and immunofluorescence workflows.

Raised in rabbit and purified as an unconjugated polyclonal reagent, the antibody is supplied as a 100 µl vial suited to routine immunodetection experiments. It is reactive with human DRD3 and intended for research use only in studies of neuropsychiatric disease, receptor pharmacology, and GPCR signal transduction. Investigators examining schizophrenia, substance addiction, and Parkinson's disease models routinely employ anti-DRD3 reagents to localize receptor distribution in tissue sections and to confirm protein abundance in cell lysates.

Application areas include Western blot analysis of DRD3 protein in membrane fractions, and immunofluorescence staining of fixed cells or cryosections to map subcellular receptor localization. The unconjugated format permits flexible pairing with secondary antibodies labelled with fluorophores or enzymes according to the chosen detection chemistry. For best stability, store at -20°C and prepare aliquots to limit freeze-thaw cycles. Each vial is provided by Antibodies.com as a primary antibody reagent for laboratory research applications.