Anti-DRD1 Antibody

Raised in rabbit against the Dopamine Receptor D1 (DRD1), this unconjugated polyclonal antibody from Antibodies.com supports neuroscience and receptor-biology workflows requiring detection of the D1 dopamine receptor across human, mouse, and rat samples.

DRD1 is a G protein-coupled receptor expressed in the central nervous system, where it mediates dopaminergic signaling linked to motor control, reward processing, and cognitive function. The reagent is supplied at 1 mg/ml in PBS containing 0.1% sodium azide and 50% glycerol, a stabilizing matrix that preserves activity across repeated freeze-thaw cycles when small aliquots are prepared.

Validated applications include Western Blot (WB) for resolving the receptor band from cell or tissue lysates and Immunofluorescence (IF) for visualizing receptor localization in fixed cells and brain sections. The unconjugated format offers flexibility to pair this reagent with fluorescent, HRP, or biotin-conjugated secondary reporters depending on the read-out desired. The 100 ul vial is sized for multiple staining or blotting experiments, and aliquoting on first use is recommended to limit handling of the bulk stock.

Reported reactivity with mouse and rat orthologues supports translational studies using rodent models of neurological disease, including Parkinson's disease, schizophrenia, and addiction research, where D1 receptor expression and modulation are primary experimental endpoints.