Anti-Doublecortin Antibody

The Doublecortin (DCX) protein is a microtubule-associated phosphoprotein essential for neuronal migration and cortical layering during central nervous system development, and it is widely recognized as a marker of newborn and migrating neurons in studies of adult neurogenesis. This unconjugated rabbit polyclonal reagent from Antibodies.com is raised against DCX and has been validated for western blot, immunohistochemistry, and ELISA workflows, with demonstrated reactivity against human, mouse, and rat samples.

Supplied as 100 µl of polyclonal antiserum suitable for immunolabeling of developing brain tissue and neural progenitor populations, the antibody supports research applications including characterization of neural stem cell differentiation, assessment of hippocampal subgranular zone neurogenesis, and investigation of lissencephaly-associated DCX mutations. The unconjugated format allows flexibility for downstream detection, and the polyclonal nature provides recognition of multiple epitopes on the DCX protein, making it a practical choice for laboratories probing developmental neurobiology, adult plasticity, and disease models involving cortical malformation.