Anti-DOK3 Antibody

DOK3 (Docking Protein 3) is a cytoplasmic adapter protein expressed predominantly in hematopoietic lineages, where it modulates downstream signaling from Src-family kinases and immune receptors. This unconjugated rabbit polyclonal IgG reagent from Antibodies.com selectively detects human DOK3 in Western blot and immunohistochemistry workflows, making it a practical tool for studies of B-cell receptor signaling, lymphocyte activation, and innate immune regulation.

The antibody is supplied as 50 µl of liquid stock, sufficient for multiple blotting membranes or IHC sections when titrated against endogenous target levels. Researchers investigating DOK3-mediated negative feedback in signaling cascades, or profiling expression in lymphoid tissue sections, can apply this reagent to confirm transcriptional and post-translational regulation events. Recommended handling includes brief centrifugation before opening and storage at -20 degrees C in working aliquots to preserve activity across freeze-thaw cycles; avoid repeated freeze-thaw of the original vial, and protect from light during short-term bench use.