Anti-DOC-1 Antibody

DOC-1 (also known as CDK2AP1) is a tumor suppressor protein originally identified through deletion mapping in oral cancer studies. It modulates cell cycle progression through direct interaction with cyclin-dependent kinase 2 and the DNA polymerase alpha/primase complex, making it a relevant target for cancer biology and cell proliferation research.

This polyclonal antibody from Antibodies.com is raised in rabbit and supplied as an unconjugated reagent at a 100 µL pack volume. It recognizes the human and mouse DOC-1 protein and has been validated for western blot (WB) and ELISA applications, supporting studies into gene regulation, oral squamous cell carcinoma models, and cell cycle checkpoint analysis.

For storage, the antibody should be kept refrigerated to preserve affinity and reactivity over multiple freeze-thaw cycles. Researchers commonly dilute the reagent in appropriate buffers for immunoblotting lysates from cultured mammalian cells, and the polyclonal format enables recognition of multiple epitopes on the target protein, increasing signal robustness across experimental conditions.