Anti-DNMT3L Antibody

The polyclonal antibody from Antibodies.com targets DNMT3L (DNA methyltransferase 3-like), a catalytically inactive regulatory factor that cooperates with DNMT3A and DNMT3B to establish DNA methylation patterns during gametogenesis and early embryonic development. Raised in rabbit and supplied at 100 µl per vial, this unconjugated reagent is validated for western blot and immunofluorescence workflows on human samples. DNMT3L is most prominently expressed in germ cells and embryonic stem cells, and the antibody is commonly applied to studies of genomic imprinting, X-chromosome inactivation, transposon silencing, and infertility-related chromatin remodeling. Researchers investigating epigenetic reprogramming in primordial germ cells or paternal methylation establishment rely on this reagent to confirm protein expression across developmental stages.