Anti-DNMT3A Antibody

This polyclonal antibody from Antibodies.com targets DNMT3A (DNA methyltransferase 3A), a de novo methyltransferase that establishes CpG methylation patterns during embryonic development, genomic imprinting, and X-chromosome inactivation. The unconjugated reagent is presented at 1 mg/ml in PBS buffer containing 0.1% sodium azide and 50% glycerol, supplied as a 100 µl vial for multiple experiments.

Validated for Western Blot, Immunohistochemistry, and Immunofluorescence applications, this primary antibody detects endogenous DNMT3A in human, mouse, and rat samples. Investigators use it to study DNA methylation dynamics in stem cell biology, hematopoiesis, and cancer models, where recurrent DNMT3A mutations are linked to acute myeloid leukemia and other hematological malignancies.

For best results, store at -20°C in working aliquots to preserve antibody activity and minimize freeze-thaw cycles. Intended for research use only.