Anti-DNM2 Antibody

The Antibodies.com polyclonal antibody recognizes Dynamin-2 (DNM2), a ubiquitously expressed ~98 kDa GTP-binding protein required for clathrin-mediated endocytosis and vesicle scission from the plasma membrane.

Beyond membrane fission, Dynamin-2 contributes to actin cytoskeleton remodeling, centrosome function, and actin comet formation on endosomes, connecting it to studies of cell motility, organelle dynamics, and receptor internalization.

Raised in rabbit and supplied as an unconjugated 100 µl liquid reagent, this polyclonal antibody is validated for Western blot and immunohistochemistry applications on Human, Mouse, and Rat samples, supporting reproducible detection of endogenous protein across common model systems.

Investigators working on centronuclear myopathy, Charcot-Marie-Tooth neuropathy, or general endocytic trafficking can use this DNM2 reagent to quantify protein levels in tissue lysates by WB and to map spatial expression patterns in fixed sections by IHC.