Anti-DNM1 Antibody

Dynamin-1 (DNM1) is a 100 kDa GTP-binding protein best known for its role in clathrin-mediated synaptic vesicle endocytosis, and this unconjugated rabbit polyclonal IgG reagent from Antibodies.com targets it for detection in human and mouse samples. The antibody is supplied as a 200 µl aliquot and is validated for western blot and immunofluorescence workflows, where it produces a clean band at the expected molecular weight in lysates from neuronal cell lines and a consistent cytoplasmic signal in fixed cells.

Because DNM1 expression is concentrated in the central nervous system, the reagent is especially useful in neuroscience research investigating neurotransmission, membrane trafficking, and the pathobiology of DNM1-related epilepsy and developmental disorders. The polyclonal IgG isotype and unconjugated format give labs flexibility to pair the reagent with secondary antibodies of their choice, while the rabbit host is well suited to standard two-step detection on immunoblots and tissue sections. Store refrigerated and protect from repeated freeze-thaw cycles to preserve titre.