Anti-DNM1 Antibody

The DNM1 gene encodes Dynamin-1, a large GTPase best known for its role in clathrin-mediated endocytosis at neuronal synapses. This rabbit polyclonal reagent targets Dynamin-1 for use in Western blot and immunofluorescence workflows, supporting studies of synaptic vesicle recycling, membrane remodeling, and intracellular trafficking in human and mouse samples.

The unconjugated IgG formulation allows flexible pairing with a wide selection of secondary detection reagents, while the polyclonal format broadens epitope coverage relative to monoclonal alternatives. Supplied as 100 µl of ready-to-use reagent in a single vial, the antibody is appropriate for probing brain and neuronal cell line lysates, fixed tissue sections, and cultured neurons, and is frequently cited in research on DNM1-linked developmental and epileptic encephalopathy.

Store refrigerated at 4°C for short-term use, or freeze in single-use aliquots at -20°C to preserve activity across multiple experiments. Each lot is validated by Antibodies.com for confirmed reactivity against Human and Mouse Dynamin-1 in WB and IF applications.