Anti-DNAM-1 Antibody

Raised in rabbit and supplied as 100 µl of unconjugated polyclonal serum, this reagent from Antibodies.com specifically detects human CD226 (DNAM-1), an activating immunoglobulin-like receptor found on NK cells, cytotoxic T lymphocytes, and platelets that engages ligands CD155 and CD112 during immune synapse formation. Validated for western blot detection of endogenous DNAM-1 in cell and tissue lysates, the antibody suits studies of NK-mediated cytotoxicity and the regulation of DNAM-1 expression in tumor-infiltrating lymphocytes, and it produces clean signals against denatured, reduced samples on standard SDS-PAGE immunoblots.