Anti-DNAM-1 Antibody

This polyclonal antibody from Antibodies.com targets DNAM-1 (CD226), an immunoglobulin-like activating receptor expressed on natural killer cells, T lymphocytes, and certain B cell populations. DNAM-1 participates in formation of the immunological synapse and mediates adhesion to its ligands CD155 (PVR) and CD112 (Nectin-2), contributing to cytotoxic activity against virus-infected and transformed target cells.

Supplied as 100 µl of unconjugated rabbit antiserum, the reagent is applicable in western blot, immunohistochemistry, immunofluorescence, and ELISA workflows. It cross-reacts with human, mouse, and monkey samples, supporting comparative immunology studies and preclinical research models that examine CD226 signaling in tumor surveillance and viral defense pathways.