Anti-DNAJC10 Antibody

Rabbit polyclonal primary antibody from Antibodies.com raised against DNAJC10 (also called ERdj5, JPDI, or macrothioredoxin), an endoplasmic reticulum-resident J-domain co-chaperone that combines a DnaJ chaperone module with PDI-like thioredoxin domains to reduce disulfide bonds on misfolded glycoproteins during ER-associated degradation. The unconjugated IgG preparation is supplied as a 200 µl liquid aliquot and is validated for Western blot detection of mouse DNAJC10, supporting studies of unfolded protein response signaling, ER stress, and protein quality control in cell biology and neuroscience workflows. Because the reagent is unconjugated, researchers can pair it with HRP-, alkaline phosphatase-, or fluorophore-conjugated secondary antibodies of their choice, and the polyclonal IgG format increases the chance of recognizing multiple epitopes along the 793-amino-acid ERdj5 protein. Storage recommendations include keeping the vial at -20 °C for long-term use, aliquoting to limit freeze-thaw cycles, and briefly holding working stocks at 4 °C. The reagent has been verified for reactivity with mouse DNAJC10; cross-reactivity with other species is not stated by the manufacturer. This product is supplied for research use only.