Anti-DNAJB6 Antibody

The Antibodies.com polyclonal reagent targets DNAJB6, a J-domain co-chaperone of the Hsp40 family implicated in protein refolding, skeletal muscle maintenance, and protection against proteotoxic stress. Raised in rabbit and supplied unconjugated at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol, the 100 µl aliquot is validated for Western blot, immunohistochemistry, and immunofluorescence workflows on human, mouse, and rat samples.

The antibody recognizes endogenous DNAJB6 across reactive species, supporting studies of muscular dystrophy-associated variants, chaperone network dynamics, and stress granule biology. The glycerol-containing formulation allows convenient storage at -20 °C with minimal freeze-thaw cycling, and the azide preservative keeps the reagent stable for routine immunolabeling without further aliquoting.

For Western blot applications, expected bands appear in the 27 to 40 kDa range depending on isoform, while immunofluorescence staining highlights cytoplasmic localization in myoblasts and other expressing cell types. Researchers investigating LGMD1D, distal myopathy, or Hsp40 co-chaperone function can deploy this reagent for both pilot characterization and broader survey work across model systems.