Anti-DNA Polymerase β Antibody

Available through Antibodies.com, this rabbit polyclonal reagent is raised against DNA Polymerase β, the small base-excision repair polymerase encoded by the POLB gene, and is supplied as a 50 µl liquid aliquot. The antibody is unconjugated and of the IgG isotype, and it is recommended for Western blot (WB) and immunohistochemistry (IHC) workflows in samples derived from human, mouse, and rat tissues, matching the reactivity profile commonly required for cross-species studies of base-excision repair and DNA damage responses. Recommended starting dilutions typically fall in the range of 1:500–1:1,000 for WB and 1:50–1:200 for IHC, allowing users to titrate the reagent to their specific sample type and detection system. The product is shipped at 4 °C; on arrival it should be aliquoted and stored at –20 °C, with repeated freeze/thaw cycles avoided to preserve activity. The polyclonal nature of the reagent makes it well suited for detecting the endogenous ~38 kDa DNA Polymerase β band in WB, and for localising nuclear POLB signal in IHC preparations. Combined with PhD-level technical support, this Antibodies.com reagent offers a reliable tool for laboratories investigating DNA polymerase β function, mutagenesis, and small-molecule inhibitor responses.