Anti-DNA pol δ3 Antibody

Polyclonal antibodies raised in rabbit target DNA polymerase delta subunit 3 (POLD3), the regulatory subunit of the high-fidelity Pol delta holoenzyme that drives eukaryotic DNA replication and DNA repair. Supplied by Antibodies.com at 100 ul per vial as an unconjugated reagent, this antibody recognizes the human, mouse, and rat POLD3 target, which migrates near 66 kDa on SDS-PAGE, consistent with its historical designation as the p66 subunit of the Pol delta complex. The reagent is validated for Western blot and ELISA workflows, and the polyclonal format allows recognition of multiple epitopes across the conserved C-terminal region shared by mammalian POLD3 orthologs. Keep the vial refrigerated; for longer-term storage, aliquot and freeze to minimize freeze-thaw loss of the active antibody. The unconjugated format gives flexibility for downstream labeling with HRP or fluorescent conjugates, supporting applications such as replication-stress studies, DNA damage response assays, and chromatin immunoprecipitation follow-up work in human cell lines and rodent model systems.