Anti-DNA-PKCS Antibody

Antibodies.com provides this rabbit polyclonal reagent raised against the catalytic subunit of DNA-dependent protein kinase (DNA-PKCS), a roughly 460 kDa serine/threonine kinase central to the non-homologous end joining pathway that repairs DNA double-strand breaks and supports V(D)J recombination in developing lymphocytes. The unconjugated antibody is supplied as a 100 µl aliquot and has been validated for western blot, immunohistochemistry, immunofluorescence, and ELISA workflows, with reactivity confirmed against human and mouse samples. Researchers studying genomic stability, DNA damage response signaling, radiosensitivity, lymphoid development, and the broader phosphoinositide 3-kinase-related kinase family will find this polyclonal reagent valuable for tracking full-length DNA-PKCS expression and post-translational modifications across cell lysates, fixed tissue sections, and cultured cells.