Anti-DMPK Antibody

Researchers studying myotonic dystrophy type 1 rely on this polyclonal primary antibody from Antibodies.com, which targets dystrophia myotonica protein kinase (DMPK) for western blot detection in human samples. Supplied as an unconjugated rabbit IgG in a 50 µl volume, the reagent supports immunoblotting of cell and tissue lysates, including skeletal muscle and cardiac preparations relevant to DM1 pathogenesis. The polyclonal format offers epitope diversity useful for capturing the full-length kinase in denatured samples, supporting investigations of CUG trinucleotide repeat expansion, MBNL1- and CELF1-mediated RNA splicing dysregulation, and downstream kinase signaling pathways. For best results, store at -20 degrees C in working aliquots and protect from repeated freeze-thaw cycles; each vial is intended for research use only and yields reproducible detection across multiple experimental runs.