Anti-DMPK Antibody

This rabbit polyclonal IgG antibody from Antibodies.com is raised against human myotonic dystrophy protein kinase (DMPK), a serine/threonine kinase encoded on chromosome 19q13.32 whose CTG trinucleotide repeat expansion in the 3' untranslated region causes myotonic dystrophy type 1 (DM1). The unconjugated reagent ships at 200 µl per vial and is validated for Western blot detection of the ~70 kDa DMPK isoform in human cell and tissue lysates. Researchers working on DM1 use it to track DMPK expression, splicing patterns and downstream signalling in skeletal muscle, cardiac and neural samples from patient biopsies and disease models. Store frozen at -20 °C in single-use aliquots to limit freeze-thaw exposure, and protect from light until first thaw. Polyclonal recognition of multiple epitopes across the kinase domain supports consistent band intensity across variable expression levels in research use only workflows.