Anti-DMP1 Antibody

Raised in rabbit and affinity-purified as a polyclonal IgG, this unconjugated DMP1 reagent targets Dentin Matrix Protein 1, an extracellular matrix phosphoprotein central to bone and dentin mineralization. Distributed by Antibodies.com, it is validated for Western blot detection of endogenous human and mouse DMP1 under reducing SDS-PAGE conditions, supporting translational work across bone and tooth development models.

Supplied as 200 µl of liquid stock in a vial, the antibody allows flexible dilution for routine immunoblotting of cell and tissue lysates. The polyclonal format provides multi-epitope recognition of full-length and processed DMP1 fragments, useful when probing osteocyte and odontoblast differentiation, phosphate homeostasis, and autosomal recessive hypophosphatemic rickets. For storage, keep the vial refrigerated at -20°C in working aliquots to preserve activity across repeated freeze-thaw cycles.

The unconjugated format leaves the choice of secondary detection to the researcher, enabling pairing with HRP, biotin, or fluorophore-conjugated secondaries for chemiluminescent or fluorescent imaging workflows. Studies commonly combine this DMP1 reagent with markers such as osteocalcin, RUNX2, and alkaline phosphatase to characterize mineralized tissue formation in vitro and in vivo.