Anti-DLX3 Antibody

Targeting the Distal-Less Homeobox 3 (DLX3) protein, this rabbit polyclonal primary antibody from Antibodies.com is supplied as 200 µl of unconjugated IgG and is validated for western blot detection in human, mouse, and rat samples. DLX3 is a homeodomain-containing transcription factor known in developmental biology for its role in craniofacial morphogenesis, tooth development, and osteoblast differentiation. Loss-of-function mutations in DLX3 are linked to tricho-dento-osseous syndrome and amelogenesis imperfecta, supporting research on dental, skeletal, and stem-cell differentiation processes.

The unconjugated format and polyclonal rabbit host give researchers flexibility to pair the reagent with their preferred HRP- or fluorophore-conjugated secondary antibodies for immunoblotting workflows on tissue lysates, primary cell extracts, or cell-line samples. Combined with standard SDS-PAGE and PVDF or nitrocellulose transfer protocols, the antibody supports expression analysis of endogenous DLX3 protein across developmental time courses, mineralizing osteoblast cultures, and comparative studies between wild-type and disease-associated models. As an unconjugated IgG preparation, it is also compatible with custom labelling for downstream assays where direct conjugation is required.