Anti-DLST Antibody

DLST (Dihydrolipoamide S-Succinyltransferase) is the E2 subunit of the mitochondrial α-ketoglutarate dehydrogenase complex, a TCA-cycle assembly that transfers a succinyl group from dihydrolipoyl to coenzyme A. This rabbit polyclonal reagent from Antibodies.com was raised against the human DLST antigen and is validated for Western blot and immunohistochemistry on human, mouse, and rat samples. It is supplied as 100 µl at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol as a cryoprotectant, and should be stored at -20 °C to preserve activity across freeze-thaw cycles; aliquoting upon first use is recommended. The unconjugated format allows direct labelling with HRP, biotin, or fluorophores for downstream detection in immunoblotting of mitochondrial fractions (DLST migrates near 49 kDa) and in formalin-fixed paraffin-embedded tissue sections probed for αKGDH complex integrity, supporting research into oxidative metabolism, mitochondrial disease, and DLST-mutated paraganglioma and pheochromocytoma models.