Anti-DLGAP5 Antibody

DLGAP5 (Discs Large Homolog Associated Protein 5), also known as HURP, is a microtubule-associated protein essential for mitotic spindle assembly, centrosome integrity, and proper kinetochore-microtubule attachment during cell division. This unconjugated rabbit polyclonal antibody from Antibodies.com is raised against human DLGAP5 and is validated for Western blot, immunohistochemistry, and immunofluorescence workflows. Supplied as 100 µL of a 1 mg/ml stock in phosphate buffered saline (PBS) containing 0.05% sodium azide at approximately pH 7.2, the reagent is intended for studies of cell cycle regulation, chromosome segregation, and tumor biology, where altered DLGAP5 expression has been reported as a prognostic marker in hepatocellular carcinoma, bladder, and lung cancers. Researchers investigating mitotic fidelity, cancer cell proliferation, or spindle assembly checkpoints can use this reagent on fixed cells and tissue sections to localize DLGAP5 at centrosomes and spindle poles during mitosis.