Anti-DLC1 Antibody

Raised in rabbit against the DLC1 tumor suppressor, this unconjugated polyclonal primary antibody is supplied by Antibodies.com as 100 µl of reagent in a single vial, validated for Western Blot and Immunohistochemistry workflows. DLC1 (Deleted in Liver Cancer 1) is a RhoGAP-family GTPase-activating protein encoded at chromosome 8p22 that is frequently deleted or epigenetically silenced in hepatocellular carcinoma, lung, breast, and colorectal tumors, making reliable detection of endogenous DLC1 protein important for cancer research. The antibody shows reactivity with human and mouse samples, supporting translational studies that span cell-line models and patient-derived tissue. Researchers commonly apply this reagent to track DLC1 re-expression after demethylating or Rho-pathway rescue experiments, and to localize the protein in tumor versus matched normal sections by IHC. Aliquot upon receipt and store at -20°C, avoiding repeated freeze-thaw cycles to preserve titer across long-running studies.