Anti-DKC1 Antibody

Manufactured by Antibodies.com, this affinity-purified Rabbit polyclonal reagent targets dyskerin (DKC1), a catalytic subunit of the H/ACA ribonucleoprotein complex involved in ribosome biogenesis and telomere maintenance. The antibody is raised against a recombinant human DKC1 immunogen and specifically detects the endogenous total DKC1 protein across validated applications including Western blot (WB), immunohistochemistry (IHC), and immunofluorescence (IF). Reactivity has been confirmed in Human, Mouse, and Rat samples, making it suitable for a broad range of translational and basic-research workflows. The unconjugated antibody is supplied at 1.0 mg/mL in a ready-to-use phosphate-buffered saline formulation (without Mg²⁺ and Ca²⁺), pH 7.4, with 150 mM NaCl, 0.02% sodium azide, and 50% glycerol as a cryoprotectant. The 50 µL pack size is shipped refrigerated from St. Louis, MO, with a typical lead time of 6–9 business days, and should be stored long term at –20 °C to preserve activity. The polyclonal nature of the reagent offers an epitope-diverse response, which is particularly advantageous when investigating post-translational modifications or splice variants of dyskerin. Recommended secondary antibodies for chromogenic, fluorescent, biotinylated, or alkaline-phosphatase detection are available within the Antibodies.com catalog (HRP, FITC, Biotin, and AP conjugates of Goat Anti-Rabbit IgG H&L), enabling flexible downstream visualization strategies in WB, IHC, and IF protocols. This product is intended for research use only and is not validated for diagnostic or therapeutic applications.