Anti-Diphenhydramine Antibody

This unconjugated polyclonal reagent from Antibodies.com is raised in rabbit hosts and selectively targets diphenhydramine, a first-generation ethanolamine-class antihistamine commonly screened in clinical toxicology, forensic chemistry, and pharmaceutical quality control workflows. The immunoglobulin fraction is purified by Protein A affinity chromatography and supplied at a 1 mg pack size suitable for routine immunoassay development.

Validation work confirms the antibody performs in ELISA protocols used to detect diphenhydramine in buffered matrices. Because the target is a small hapten rather than a full protein, the immunogen was prepared as a diphenhydramine–protein conjugate, and the resulting polyclonal pool recognizes the parent molecule along with phase-I metabolites such as desmethyldiphenhydramine. Researchers building competitive inhibition assays, calibration curves, or anti-idiotype characterization panels rely on this reagent as a capture or competitor binding partner.

On arrival, refrigerate the vial and protect from light; aliquot before freezing to limit freeze-thaw exposure of the Protein A Purified Ig Fraction. The unconjugated format allows end users to couple the antibody to HRP, biotin, fluorophores, or latex beads according to their own assay platform needs. For research use only; not intended for diagnostic or therapeutic applications.