Anti-DIDO1 Antibody

The DIDO1 (Death Inducer-Obliterator 1) protein is a nuclear factor implicated in TNF-mediated apoptosis signaling and in the maintenance of pluripotency in embryonic stem cells. This rabbit polyclonal reagent, supplied by Antibodies.com as a 100 µl liquid preparation, detects endogenous human DIDO1 in standard immunoblotting and immunofluorescence workflows.

Validated applications cover Western Blot and Immunofluorescence, making the antibody suitable for studies of programmed cell death pathways, stem cell self-renewal, and chromatin regulation. The DIDO1 gene gives rise to several isoforms—DIDO1, DIDO2, and the longer DIDO3—each with distinct roles in cellular viability; loss of DIDO3 in particular triggers apoptosis and genomic instability in pluripotent cells.

Because the polyclonal format recognizes multiple epitopes on the target, the reagent offers tolerance for minor sample variation across human cell lines. Researchers in cancer biology, stem cell research, and apoptosis pathway characterization can use this unconjugated antibody in flexible assay design, paired with a wide choice of secondary detection reagents.