Anti-DHRS2 Antibody

DHRS2 (dehydrogenase/reductase SDR family member 2), also known as HEP27, is a mitochondrial NADPH-dependent oxidoreductase involved in retinoid and short-chain carbonyl metabolism. This polyclonal antibody from Antibodies.com is generated in rabbit hosts and supplied unconjugated in a 100 µl volume, supporting Western blot and immunofluorescence workflows. The reagent reacts with Human, Mouse, and Rat DHRS2, enabling cross-species comparative studies in cell lysates and tissue samples.

On Western blot, DHRS2 resolves near its calculated molecular weight of approximately 30 kDa, providing a clear reference band for positive controls. The polyclonal nature of the antibody permits recognition of multiple epitopes on the target protein, which is valuable when studying post-translationally modified or splice-variant forms. For immunofluorescence, the unconjugated format allows flexible pairing with secondary reagents matched to specific experimental designs, including colocalization studies in mitochondria.

Investigators in mitochondrial biology, redox metabolism, and hepatocellular carcinoma research probe DHRS2 expression under basal and stress-induced conditions with this reagent. Aliquot the antibody upon arrival and store refrigerated to preserve IgG integrity; protect from light and avoid repeated freeze-thaw cycles that compromise antibody performance over time.