Anti-DHPS Antibody

This rabbit polyclonal antibody recognizes deoxyhypusine synthase (DHPS), the NAD-dependent enzyme that catalyzes the first committed step of hypusine biosynthesis on eukaryotic translation initiation factor 5A (eIF5A). Because DHPS sits at a unique post-translational modification step, this reagent is relevant to work on translational control, polyamine metabolism, cell proliferation, and HIV-1 replication biology.

The antibody is supplied as 100 µl at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol, in an unconjugated format suitable for Western blot and immunohistochemistry. It reacts with human, mouse, and rat DHPS, supporting cross-species experimental design. Aliquot upon arrival and store at -20 °C; avoid repeated freeze-thaw cycles, since the glycerol cryoprotectant helps preserve antibody integrity over long-term storage.

For Western blot, the polyclonal reagent allows detection of endogenous DHPS in cell lysates across multiple epitopes, which can be useful when working with denatured protein on membranes. For immunohistochemistry, the same reagent enables visualization of DHPS expression in fixed tissue sections, supporting studies of tissue-specific and disease-associated expression patterns. Researchers studying cancer cell growth, viral host-factor dependency, or spermidine-pathway pharmacology will find this reagent a focused tool for their workflow. Antibodies.com validates each lot to help ensure reproducible signal across experiments.